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Fundamental research

22 - 05 - 2017

Why does allergic asthma affect more women?

Allergic asthma is twice as common and more severe in women than in men.

In mice, asthma is more violent in females than in males. Male castration only, makes this difference disappear. In vitro and in vivo studies, recently published by Toulouse researchers, have shown that testosterone inhibits the development of ILC2 immune cells that are involved in asthma via their androgen receptor.

This receptor could therefore become a target for treating allergic asthma.