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24 - 05 - 2017

Vaccinating against malaria

Malaria is a parasitic disease that affects hundreds of millions of people every year and kills hundreds of thousands, mostly children. A vaccine, even only 80% effective, would eradicate the disease. But its development is difficult because the parasite is adaptable and has a complex cycle. The most predictive preclinical model is a primate model.

A new vaccine that targets two parasite proteins essential for its cycle (RON2L and AMA1) has completely protected four monkeys out of eight, and three more partially. Clinical trials should be upcoming.