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Scientific progress

21 - 03 - 2018

Stem cell therapy in cats

Stem Cell Cell Therapy has a huge therapeutic potential in veterinary medicine especially in the field of inflammatory cat diseases.
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The Journal of Feline Medicine and Surgery has published a review of medical advances expected in the field of mesenchymal stem cell therapy (MSC) in cats, as well as information on ongoing clinical research.

 


 
MSCs are most often obtained from fatty tissue. They can come from the animal that will be treated (autologous MSC) or from qualified donors (non-native MSC).
 
MSCs act on the regeneration of tissues through contact with other cells, the production of mediators, extracellular vesicles and even membrane nanotubes for the transfer of RNA and mitochondria to damaged cells. They promote the development of vessels, reduce inflammation and regulate the immune response.
 
Given the immunomodulatory properties of MSCs, they are particularly studied in inflammatory diseases:
• - gingivitis and chronic stomatitis
• - chronic or acute kidney disease
• - enteropathies
• - asthma
But other studies are ongoing in the areas of osteoarthritis and cardiomyopathies.
 
Much of the results of these studies can be transposed and advance research in comparable human diseases.
 
The main difficulties to be overcome for the use of MSCs in feline veterinary medicine are today the production and provision of optimal MSCs.

 

https://journals.sagepub.com/doi/pdf/10.1177/1098612X18758590