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Alternative methods

04 - 10 - 2018

Non-animal models and the safety assessment of chemicals

Unilever and the NC3Rs are organizing two days of workshops in London regarding the place of in vitro and in silico methods in the evaluation of the safety of chemicals.


Chemical safety assessment studies are still largely based on animal data. However the use of non-animal methods is progressing.

In vitro and in silico methods help today discover and study the mechanisms of action. When combined with estimated or measured exposure data, they may result in a reduction of the use of animal-derived data.

But there is a lack of confidence in these methods especially in the regulatory field.

The meeting organized by the NC3Rs and Unilever in London on the 10-11 December 2018 will bring together scientists, industries and authorities. They will share their experiences and knowledge on chemical safety decision-making from non-animal data, that is, obtained from in silico and in vitro studies.

The main objectives of the meeting are:

               - the presentation of concrete cases

               - raising the authorities' awareness on non-animal methods

               - the identification of scientific problems

               - encouraging the collaboration of the sectors of activity concerned.