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04 - 11 - 2016

A new step towards treating Alzheimer’s disease

Amyloid plaques are associated with Alzheimer’s disease. Blocking the formation of these plaques may treat the disease. A substance called Verubecestat, is currently producing some very interesting results on the matter.  

Designed from the structure of brain proteins, this product has been shown to be effective and specific on in vitro human tissues. In vivo tests in rats and macaques have shown that can actively reduce amyloid plaques without any toxicity and side effects, including on the nervous system. A discoloration of the fur coat was observed in mice and rabbits, but not in macaques (the rats were albinos).

The first human trials in healthy humans and patients have confirmed the effect of the drug on the amyloid plaques, while being highly tolerable. A two-year trial on 1500 patients with early symptoms of the disease has started and hopes to discover if this substance can truly recede the symptoms of Alzheimer’s disease.