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Alternative methods

02 - 10 - 2017

The National Institute of Health project for an in vitro human retina

The first phase of the North American human in vitro retina project has been achieved.


Nearly 300 million people in the world suffer from visual disabilities and among these, 39 million are blind. These vision losses are often related to retina diseases (AMD, glaucoma, diabetic retinopathy).


Better study models accelerate medical progress. This is why research has been trying for decades to build human organs or parts of organs in the laboratory. This requires having enough knowledge and mastering new technologies.


In the USA, the National Eye Institute, an NIH institute, opened in May 2017 the 3-D Retina Organoid Challenge or 3- D ROC. This three-year competition hopes for the creation of a miniature in vitro human retina, in the form of an organoid.


Today a team has received a first endowment of $ 90000 for its project. They hope to serigraph neuronal progenitors derived from adult neurons on a support.




The project appears to be sufficiently scalable, efficient and reproducible to allow for the very large number of tests required for the selection of substances for medical treatment.


Five other proposals received honourable mentions. For all these projects, the next step is the publication of scientific results.