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Scientific progress

01 - 08 - 2016

Metabolites from microbiota protect against diabetes and obesity

A Franco-Swedish study examined the mechanisms that may explain why high-fibre foods protect us from obesity and diabetes. Succinate, a propionate precursor, a product of fibres being fermented by the microbiota, can be converted into blood glucose. Even fed a diet rich in fats and sugars, mice are less likely to become fat. They are also more sensitive to insulin. Published in Cell Metabolism, this study has also revealed the importance of intestinal glucose in blood sugar regulation.