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Animal research

28 - 02 - 2017

How insects become resistant to toxic products

Researchers have identified the metabolic pathways and genes involved in the natural resistance of some flies, Drosophila, to a lethal fungal toxin, alpha-amanitine. This resistance appears to be related to insecticide resistance.

They studied the genome of 180 differently resistant species and found out how flies manage to eliminate toxins from their bodies. At the same time, they discovered that the metabolic pathway responsible for this resistance, called mTOR, also exists in mammals and humans. Human health might be impacted by this work.