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Health, Scientific progress

10 - 08 - 2017

How the immune system preserves male fertility

Spermatozoa appear in the testicles only at puberty, which makes them susceptible to be identified as foreign and destroyed by the immune system. How does our organization avoid this destruction?


An Inserm team in Marseille studied in mice how certain immune cells, macrophages, protect spermatozoa and the production of testosterone within the testicles by diffusing specific molecules to other actors of the immune system. They have already discovered that these macrophages once established in the testicle remain there all their lives.


This fundamental work will eventually help consider new treatments for some cases of male infertility.