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Alternative methods

22 - 11 - 2016

How do mice help with the creation of in vitro human organs

French (INSERM), North American and Australian researchers have for the first time succeeded in building in vitro a piece of human intestine containing a nervous network, from stem cells. This intestinal tissue, implanted in immunosuppressed mice (to avoid rejection), showed signs of contractile waves, proving the success of the construct.

This complex construct will make it possible to better study how the human intestine functions (physiology) and some human diseases (pathology) of the intestine. It is a new research tool. But before you consider creating and grafting a human gut into people in need, much work still remains to be done.