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13 - 06 - 2017

Anti-inflammatory drugs prevent injured muscle repair

Researchers at Stanford University in the United States have discovered that prostaglandin E2 (PGE2) that is produced as a result of muscle injury activates the stem cells that will repair the muscle.

They also discovered that anti-inflammatory drugs such as aspirin or ibuprofen block the production of PGE2 and thus prevent muscle repair, which results in a reduction in its strength. These studies were carried out in vitro and in mice.

Beyond the difficult choice that injured athletes may have to take (taking or not taking an anti-inflammatory drug), this discovery opens perhaps the way to the discovery of an innovative way to stimulate muscle stem cells and tissue regeneration.