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Alzheimer

« Alzheimer’s disease is a slow degeneration of neurons, which starts in the hippocampus and then extends to the rest of the brain. It affects short-term memory, executive functions and orientation in time and space. Patients progressively lose their cognitive capacity and their autonomy. » Source: INSERM  

 

In 2014, there were 900 000 patients in France suffering from Alzheimer’s disease. It is estimated that there will be 1,3 million by 2020. There is still no treatment.

 

Research is essential. It focuses on knowing the brain and how it ages and relies on cellular models, animal studies and clinical studies. Therapeutic targets have been discovered and clinical trials are underway. Today, immunotherapy seems to be the best option.

Animal species used: mouse, rat, monkeys (macaque and mouse lemur)